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A slow and steady revolution is sweeping the market for erectile dysfunction drugs – Cialis. Most people may not even be aware of it. Lilly ICOS, the pharmaceutical alliance, which launched the blockbuster drug Cialis, announced that the drug has achieved 1 billion dollars in global sales since launching in Europe less than two years back. In fact Cialis has become the top Erectile Dysfunction treatment in France, since January 2005, based on the latst market data, easily overtaking Viagra, the first brand to be launched in this market. It is also doing very well in United Kingdom, Italy, Germany, United States, Canada, Australia, Mexico and Brazil. So much so that a Lilly ICOS press release contained these words from Rich Pilnik, President of Lilly's EMEA region "We are very pleased with the performance of Cialis and the steady development of the brand since its launch two years ago. Millions of men suffer from ED and the growth of the market demonstrates that patients are speaking to their healthcare providers about ED and seeking treatment options." Not only has Cialis been able to expand the market but it has also eaten heavily in the market share of Viagra from Pfizer, the first drug to be launched in this market and Levitra from Glaxo-Bayer-Schering Plough. In fact Cialis was the second PDE5 inhibitor drug to become available in Europe. It is currently promoted in approximately 100 countries including the United States, Australia, Brazil, Mexico, Canada and across Europe and Asia for Erectile Dysfunction. According to Paul Clark, Chairman and Chief Executive Officer of ICOS Corporation. "Passing the $1 billion mark is an important milestone for Lilly ICOS and a great accomplishment for the Cialis team. Since 2003, men with erectile dysfunction have had a choice of oral treatments for their condition - a condition which may impact on relationships and daily life." Beyond all the hype and the jubilation is the sheer superiority of Cialis over all the other drugs available in this indication. To understand the benefits of Cialis, we need to firstly understand this complex condition. Erectile Dysfunction or Impotence is defined as the inability to ensure and maintain an erection sufficient for sexual intercourse. ED affects an estimated 180 million men worldwide . 90 percent of ED cases are related to a physical or medical condition, such as diabetes, cardiovascular diseases, and prostate cancer treatment, while 10 percent are due to psychological causes . In many cases, however, both psychological and physical factors contribute to the condition. Where physical factor play an important role PDE-5( Phosphodiaterase) inhibitors have a significant role to play. These include drugs like Sildenafil (Viagra) and Vardenafil(Levitra). But none are as good as Tadalafil(Cialis). Why? Firstly let’s understand how PDE-5 inhibitors work. They work by inhibiting the enzyme phosphodiasterase-5 which is responsible for degrading another enzyme called cGMP(cyclic Guanosine Mono Phosphate) which through a series of reactions is responsible for the synthesis of nitric oxide. Nitric oxide is an important vasodilator responsible for dilation of the blood vessels that supply blood to the penis. Thus, there is an increase in the blood supplied to the penis and this increased blood engorges the penis and leads the formation of an erection through hydraulic pressure. All PDE-5 inhibitors work in the same way but because they are different molecules, they also have different properties. The body quickly eliminates both Sildenafil and Vardenafil. Therefore their action lasts for only 4 hours, while Tadalafil(Cialis) is absorbed and eliminated slowly therefore it remains in the body for a longer period of time. Therefore its duration of action is 9 times that of other drugs - 36 hours. This ensures that Cialis will act over a whopping 36 hours and any patient on Cialis does not need to have hurried sex , but sex at his or his partner’s leisurely pace. That is why Cialis has been nicknamed as “Le Weekend Pill” in France. It allows the man to relax with his partner and have spontaneous sex. Also other drugs like Viagra act on the enzyme PDE-6, which is found in the eyes, leading to bluish discolouration of vision, which will not occur with Cialis. Cialis can be taken with a 100% fat meal and there will be no change in it’s action. The same is not true for Sildenafil or Vardenafil, which are affected by food. All this makes Cialis currently the best drug for erectile dyfunction. What further adds to it’s appeal are programmes like “The Cialis Promise” from Lilly ICOS which guarantees free trial with a rival drug in case Cialis does not work. With this kind of confidence oozing from Lilly ICOS, there is reason to believe in the promise of Cialis. Cialis is available at any neighbour chemist on providing a doctor’s prescription or one can buy Cialis online. An online prescription is generated on filling a short form and on payment through credit card, one can be rest assured of getting Cialis discreetly. What more cheap generic Cialis is also available online. This will further reduce your medical bills. The low cost is like an icing to the Cialis cake or pudding for that matter . 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Hypertension (high blood pressure) affects about 50 million individuals in the United States. Of these, about 70% are aware of their diagnosis, but only about a half of those are receiving treatment and only 25% are under control using 140/90 as the cutoff guideline. A new category has been designated as “pre-hypertension” and that is when the blood pressure is 120-139 systolic over a diastolic of 80-89. Blood pressure readings vary greatly in individuals depending on the time of day, where the patient is at when they get it checked, how soon they have eaten, smoked, or even drank a cup of coffee. A diagnosis of hypertension should not be based on one reading unless that reading is extremely high and/or there is evidence of end organ damage such as renal (kidney) or heart involvement. The diagnosis of hypertension should be made only after two or more readings on two or more office visits. The frightening thing about hypertension is that it usually does not cause any symptoms. Unless you are getting your blood pressure regularly checked, you could be walking around for years with elevated blood pressure and not know it. That is why it is referred to as the silent killer. If you are being diagnosed with hypertension for the first time, there are certain tests that your doctor should order. Blood tests including a complete blood count, fasting lipids (cholesterol), fasting blood sugar, renal (kidney) functions, liver functions, and electrolytes (potassium, sodium levels), along with a urinalysis should be checked. You should also have a chest xray to check for enlargement of your heart which can occur over time with hypertension, and an electrocardiogram to check for any cardiac (heart) abnormalities. Treatment of hypertension is multi-faceted. Lifestyle modification should include smoking cessation, daily exercise implementation, dietary changes, alcohol moderation, and sodium restriction. One should consume a diet with plenty of vegetables, fruit, and low dietary fat. Exercise should consist of daily brisk exercise such as walking at least 30 minutes per day most days of the week. A 10% weight loss can make a significant difference in blood pressure readings. Alcohol consumption should be limited to no more than two drinks per day (24 oz. of beer, 10 ounces of wine, or 3 oz. of “hard” liquor such as gin, whiskey, or vodka). You should also reduce salt intake to no more than 2.4 grams of sodium per day. I tell my patients not to add any salt to any foods and restrict high sodium items. If your blood pressure is not extremely elevated, say in the 145/95 range, and you are determined to make substantial lifestyle changes, then perhaps you can bring your blood pressure down to normal range with these measures. I always give my patients in these situations the option to try lifestyle modifications first if they wish as long as their blood pressure is not seriously high. Most patients, however, end up having to take a medication for their hypertension. There are a wide variety of medications available that we can prescribe and the majority of patients require more than one type of medication to reach a desired blood pressure goal. Discuss with your physician the side effects of each and what would be the most suitable medication for you. Medications have come a long way for treating blood pressure in the past twenty years and the side effect profiles are much more favorable than they used to be overall. I have found that a good portion of my patients have an aversion to taking a pill everyday for the rest of their lives. But what I tell them is that they ought to look at it like a vitamin, or better yet, an insurance policy. If it prevents you from having a heart attack or stroke and from either premature death or perhaps becoming confined to a wheel chair and not being able to take care of yourself, then taking a daily pill or two should not even be an issue. Don’t be afraid to talk to your doctor about treatment and asking about the tests I have discussed. Most importantly, please get into your physician at least once a year to get your blood pressure taken, and more often if it has been on the high end of normal. Copyright 2006 Ted Crawford pnis enlargement fact penile enlargment cream magna rx results free penis enargement video penile enlargement operation cheap pennis enlargement free penis enlagement manual penile enlargement exercise bottle vimax pills

Testosterone deficiency, also known as hypogonadism, is a condition in which the testes are unable to produce enough testosterone to fulfill the body's needs. Testosterone deficiency has many possible causes, including genetic abnormalities, injury to the testes, and being on certain medications. Normal aging also may play a role in the decline of male testosterone levels. It is also known as low testosterone. The testes produce testosterone regulated by a complex chain of signals that begins in the brain. This chain is called the hypothalamic-pituitary-gonadal axis. The hypothalamus secretes gonadotropin-releasing hormone (GnRH) to the pituitary gland in spurts, which trigger the secretion of leutenizing hormone (LH) from the pituitary gland. This hormone stimulates the Leydig cells of the testes to produce testosterone. Normally, the testes produce 4-7 milligrams (mg) of testosterone each and every day. After puberty, testosterone production increases rapidly, and will decrease rapidly after age 50. Recent estimates show that approximately 13 million men in the United States experience testosterone deficiency and less than 10-percent receive treatment for the condition, which is growing in cultural acceptability. Studies also have shown that some men with obesity, diabetes, or hypertension may be twice as likely to have low testosterone levels, though as stated, low testosterone and testosterone deficiency can be caused by taking certain medications, chemotherapy, infections and other basic causes. Signs of testosterone deficiency depend on the age of onset and the duration of hormonal deficiency. Congenital testosterone deficiency is usually characterized by underdeveloped genitalia, and sometimes even undeterminable genitalia. Acquired testosterone deficiency that develops near puberty can result in enlargement of breast tissue (gynecomastia), sparse or absent pubic and body hair, and underdeveloped penis, testes, and muscle. Adults may experience diminished libido, erectile dysfunction, muscle weakness, hair loss, depression, and other common mood disorders. pnis enlargement surgery photo penis enargement excercises do penis enargement pills work natural penis enlargment exercise pennis enlargement before and after photo penis enlarement surgeon penile enlargment video penis enhancement tool bottle vimax pills

"Vanilla" is a term used frequently by those, into more or less alternative lifestyles, for those, who - according to them - are not. The question however is, does "vanilla" actually exist and isn't vanilla actually the new sexual minority? Let's face it: the we-get-married-live-happily-ever-after have-sex-2.5-times-per-week couple is rapidly becoming a rare phenonomemum in our modern society. Sex before marriage (almost unthinkable fifty years ago) is the current norm. Usually with multiple partners. Especially in the United States teenage mothers still in high school is no longer an exception (not meaning to say that this a a good sign!). More than half of the United States marriages end up in a divorce and this has brought us a new term: "serial monogamy". "Till death do us part" is a vow not many people will stick to these days and if they do it is far from uncommon to engage in such things as threesomes, swinging or simply do what modern day therapists call "spicing up your sexlife". Is all this "uncommon" or "abnormal"? In terms of evolution actually not. In the end the human species is a mamal and monogomous mamals are indeed very rare. To a point there is evolutionairy logic to becoming pregnant as soon as you can. Why else would nature create fertility at a young age? Give a bonobo (an ape) a pencil and it is likely to draw a penis (yes they can and will, as scientific research has proven). And on the evolutionary calender of mankind things such as monogamy or even marriage make up for less than the last five minutes of that calender. Can you honestly say you have never engaged in anything kinky? There is no scientific research to provide a solid answer to that question. But my guess is that in our modern Western society very few people can honestly say they never have. In the current Internet age many - if not most - people at the very least have taken a (sneak)peak at porn-sites, engaged in an erotic chat or even exchanged some steamy email. Exposed belly buttons and navel piercings are common fashion statements and so are spiked leather collars, high heels, short skirts, revealing blouses and push-up bras. Not mention botox and breast implants. Yes, a breast implant is a form of kinky sex. In the kinky world it is called body manipulation and in fact no different from a tattoo, a piercing, a branding or a scar. What actually is the difference between wearing make up and wearing a sexy leather skirt? The answer is: your own perception - nothing else. There's an old joke: "A dirty mind is a joy forever". As in most jokes there is wisdom in this one. The brain is the biggest sex organ. Some would argue it actually is the only one. And that is the whole point. Your own perception is what drives you. And if you want to "hip", "avant garde" or tendsetter? Well, maybe becoming "vanilla" again might be a wise choice. manual penis enhancement pro solution pills review home penile enlargment prosolution penis elargement pills penis enlarement manual pennis enlargement exercise free magna rx pnis enlargement surgery photo bottle vimax pills

Breast implants are medical devices that typically consist of a silicone elastomer shell filled with saline or silicone gel. The first silicone breast implants are developed by two plastic surgeons from Texas: Frank Gerow and Thomas Cronin. The implants are textured silicone bags and can be filled with saline, which is salt water, or silicone gel and they are smooth or textured silicone bags that can be round (dome shaped) or breast shaped (anatomic). Shaped breast implants are designed to reflect the slope of the breast. The breast implants are usually quite successful at making the breasts larger and fuller. And just about 80% of breast implants are for cosmetic reasons. If your doctor tells you that breast implants are proven safe, ask for a copy of any report that studied women with implants for at least 10 years. There is strong evidence that both saline and silicone breast implants can cause local complications including swelling and gel leakage. One study says silicone breast implants do not cause systemic illness. Like silicone breast implants, saline implants consist of a rubber like silicone shell. It should also be said that studies have shown that most women who get breast implants are happy with the results. Breast implants are considered by the FDA as medical devices and if the FDA approves silicone breast implants, many young women will get them. While this is not a final approval, it does mean that the FDA may soon allow silicone gel breast implants to return to the US. Silicone breast implants were removed from the market in 1992, and recently reintroduced. Health Canada has lifted restrictions on silicone breast implants, giving two manufacturers permission to market their products in Canada. The background is that silicone breast implants have been linked to a variety of illnesses, the most controversial of which are connective-tissue diseases and symptoms. One should also notice that there has been a great deal of controversy regarding the safety of silicone breast implants but they have been marketed in the United States since 1963. The Canadian government has now reversed a partial ban placed more than 14 years ago over health concerns linked to silicone breast implants. New research suggests that silicone breast implants could be replaced by tissue grown from a person´s own stem cells within a decade. What are the risks with these implants? Well, some studies indicate that women with cosmetic breast implants have a significantly increased risk of suicide. A long-term study suggests that cosmetic breast implants do not increase the overall risk of getting cancer. Although breast enlargement is a simpler form of surgery than other cosmetic breast procedures and complications can occur. The risk is about 1% but if it occurs the implants will have to be removed. There is a very slight risk that breast implants may rupture during a mammogram and the longer you have an implant, the greater the risk it will leak or rupture. As it now is the most commonly performed cosmetic operation not performed under local anaesthesia the results are very good. As with any surgery you should have a comprehensive, informative and understandable consultation with the doctor performing the surgery. That is crucial.